pharmaceutical intermediates definition

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While folic acid is generally considered safe, excessive intake may lead to potential risks. High doses of folic acid can mask vitamin B12 deficiency symptoms, which could result in neurological damage if the underlying B12 deficiency is not addressed. It is crucial to strike a balance and avoid unnecessary high doses unless recommended by a healthcare professional.

The compound displays interesting thermal stability, making it suitable for processes that require high temperatures. Moreover, its low freezing point allows it to remain in a liquid state under various conditions, which is beneficial for industrial handling and application.


Tofacitinib is primarily used to manage conditions characterized by chronic inflammation. In rheumatoid arthritis, it helps alleviate pain, stiffness, and swelling, thereby improving the quality of life for patients. Similarly, in ulcerative colitis, it assists in achieving remission and maintaining symptom control.


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The active ingredient in erythromycin is erythromycin itself, which is derived from the bacterium Saccharopolyspora erythraea (formerly known as Streptomyces erythreus). The compound works by inhibiting bacterial protein synthesis, which ultimately leads to the cessation of bacterial growth and replication. Beyond the active ingredient, erythromycin formulations often include several excipients or inactive ingredients that aid in the medication's stability, absorption, and overall efficacy.


Furthermore, the polar nature of the oxygen atom introduces asymmetry to the compound, potentially imparting unique properties that influence its reactivity and interaction with other substances. This molecular configuration can allow for a diverse range of applications, particularly where non-reactivity is prized.


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